// a href = ./ //

ST. LOUIS (AP) -- Matt Adams and Jaime Garcia did just fine for the St. Louis Cardinals on Sunday.

Too bad for them, the bullpen didn't fare so well. The Milwaukee Brewers rallied late and Jonathan Lucroy's home run in the 10th inning gave them a 4-3 win.

Garcia pitched seven innings of shutout ball, working around seven hits and two walks.

"As Jaime pitched as well as he did, it's tough to see it end that way," St. Louis manager Mike Matheny said.

The Brewers had gone a team-record 32 innings without scoring before Ryan Braun hit a two-run homer off reliever Trevor Rosenthal in the eighth that made it 3-2.

Braun's second home run of the season snapped a 39-inning shutout streak for St. Louis pitchers. The Brewers had not scored since the second inning Tuesday against the Cubs.

Matheny would have preferred to let the Cardinals closer for now, Mitchell Boggs, pitch the ninth with a cushion. But after Braun connected off Rosenthal, he did not have that luxury.

"The situations you get put into, you got to figure out a way to get out of them," Matheny said.

Milwaukee tied it in the ninth on a leadoff single by Carlos Gomez and an RBI double by Yuniesky Betancourt. Boggs left without retiring a batter and blew his second save in five chances.

"Days like today are tough," Boggs said. "I'm not going to stand here and act like it doesn't affect me, because I care. I wanted to help us win a ballgame today. I didn't do that. If you're a professional, you show up the next day and do your job."

After retiring Rickie Weeks on a fly to start the 10th, Fernando Salas (0-2) gave up Lucroy's first home run of the season.

Brandon Kintzler (1-0) pitched a scoreless ninth and got the first out in the 10th. Burke Badenhop retired pinch-hitter Carlo Beltran on a grounder for the final out and his first save.

Adams had another big day in the loss, hitting a home run and a single. He has homered in three straight games and has a hit in all five games he has played.

Adams is batting .611 (11-for-18) with three homers and eight RBI.

"I'm seeing it well, and feeling good at that plate," Adams said. "It all comes back to the work I'm getting in the cage before the game and making sure I watch the video and I'm prepared."

Matt Holliday had an RBI single and Yadier Molina an RBI double for the other St. Louis runs.

The Cardinals broke through against Marco Estrada with four consecutive two-out hits in the third, including an RBI single by Holliday and an RBI double to the gap by Molina. Allen Craig was thrown out at the plate trying to score on Molina's hit.

Adams made it five straight hits when he led off the fourth with a 419-foot homer to center that made it 3-0.

NOTES: Molina received his fifth consecutive Gold Glove award before the game. ... On Saturday, Adam Wainwright became the first St. Louis pitcher with a shutout in which he struck out at least one batter in every inning since Bob Gibson accomplished the feat on June 17, 1970, at San Diego.

© 2013 THE ASSOCIATED PRESS. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED. Learn more about our PRIVACY POLICY and TERMS OF USE.

PYONGYANG, North Korea (AP) — North Korea on Tuesday urged all foreign companies and tourists in South Korea to evacuate, saying the two countries are on the verge of a nuclear war. The new threat appeared to be an attempt to scare foreigners into pressing their governments to pressure Washington and Seoul to act to avert a conflict.

Analysts see a direct attack on Seoul as extremely unlikely, and there are no overt signs that North Korea's army is readying for war, let alone a nuclear one.

In Pyongyang, there were no signs of a military buildup. Scores of people were armed on a cold spring day with shovels, not guns, and were busy planting trees as part of a forestation campaign. The national flag fluttered across the city as North Korea marked the 20th anniversary of late leader Kim Jong Il's appointment as chairman of the National Defense Commission, and workers began preparing the city for the April 15 birthday of late President Kim Il Sung.

South Korea's military has reported missile movements on North Korea's east coast, but nothing pointed toward South Korea.

"The situation on the Korean Peninsula is inching close to a thermonuclear war due to the evermore undisguised hostile actions of the United States and the South Korean puppet warmongers and their moves for a war against" the North, said a statement by the North Korean Asia-Pacific Peace Committee, an organization that deals with regional matters.

The statement is similar to past threats that analysts call an attempt to raise anxiety in foreign capitals.

Analysts see the threats of war as a bid to win Pyongyang-friendly policy changes in Seoul and Washington. Last week, North Korea told foreign diplomats in Pyongyang that it will not be able to guarantee their safety starting Wednesday. It is not clear what significance that date holds.

Observers also say the torrent of North Korean prophecies of doom and efforts to raise war hysteria are partly to boost the image and military credentials of young leader Kim Jong Un.

Air Koryo's daily flight from Beijing was only half full on Tuesday. Flight attendants in red suits and blue scarves artfully kept in place by sparkling brooches betrayed no sense of fear or concern.

Among the tourists who arrived Tuesday was Mark Fahey, a biomedical engineer from Sydney, Australia, who said he thought a war was "pretty unlikely."

Fahey, a second-time visitor to North Korea, said he booked his trip to Pyongyang six months ago, eager to see how North Korea might have changed under Kim Jong Un. He said he chose to stick with his plans, suspecting that most of the threats were rhetoric.

"I knew that when I arrived here it would probably be very different to the way it was being reported in the media," he told The Associated Press at Pyongyang airport. He said his family trusts him to make the right judgment, but "my colleagues at work think I am crazy."

He said he took no special precautions. "I haven't brought anything at all - just a camera," he said with a laugh. But he noted that several other tourists who had been slated to travel with his group had canceled their journeys.

Chu Kang Jin, a Pyongyang resident, said everything is calm in the city.

"Everyone, including me, is determined to turn out as one to fight for national reunification ... if the enemies spark a war," he said, using nationalist rhetoric employed by many North Koreans when speaking to the media.

South Korean President Park Geun-hye, who has sought to re-engage North Korea with dialogue and aid since taking office in February, expressed exasperation Tuesday with what she called the "endless vicious cycle" of Seoul answering Pyongyang's hostile behavior with compromise, only to get more hostility.

U.S. and South Korean defense officials have said they've seen nothing to indicate that Pyongyang is preparing for a major military action, and there was no sign of an exodus of foreign companies or tourists from South Korea.

Still, the United States and South Korea have raised their defense postures, as has Japan, which deployed PAC-3 missile interceptors in key locations around Tokyo on Tuesday as a precaution against possible North Korean ballistic missile tests.

In Rome, U.N. Secretary-General Ban Ki-moon described the tensions on the Korean Peninsula as "very dangerous" and said that "any small incident caused by miscalculation or misjudgment" may "create an uncontrollable situation."

Also Tuesday, North Korea pulled out more than 50,000 workers from the Kaesong industrial park, which combines South Korean technology and know-how with cheap North Korean labor. It was the first time that production has been shut down at the complex, the only remaining product of economic cooperation between the two countries that began about a decade ago when relations were much warmer.

Other projects from previous eras of cooperation such as reunions of families separated by war and tours to a scenic North Korean mountain stopped in recent years.

___

Associated Press writers Hyung-jin Kim in Seoul, South Korea, and Nicole Winfield in Rome contributed to this report.

___ Follow AP's Korea bureau chief on Twitter at twitter.com/newsjean.

WASHINGTON (AP) -- Talk about a comeback: A treatment pulled off the market 30 years ago has won Food and Drug Administration approval again as the only drug specifically designated to treat morning sickness.

That long-ago safety scare, prompted by hundreds of lawsuits claiming birth defects, proved to be a false alarm.

Monday's FDA decision means a new version of the pill once called Bendectin is set to return to U.S. pharmacies under a different name - Diclegis - as a safe and effective treatment for this pregnancy rite of passage.

In the intervening decades, the treatment is widely believed to have undergone more scrutiny for safety than any other drug used during pregnancy.

"There's been a lot of buzz about this. Nothing better has come along" to treat morning sickness in those 30 years, said Dr. Edward McCabe, medical director for the March of Dimes, who welcomed the step.

"We know safety-wise, there's zero question," said Dr. Gary Hankins of the University of Texas Medical Branch in Galveston, who headed one of the company-financed studies of Diclegis that led to its approval.

U.S. sales of Diclegis are expected to begin in early June, according to Canada-based manufacturer Duchesnay Inc. The company has long sold a generic version of the pill in Canada under yet another name, Diclectin.

For all the names, the main ingredients are the same: Vitamin B6 plus the over-the-counter antihistamine doxylamine, found in the sleep aid Unisom. U.S. obstetricians have long told nauseated pregnant women how to mix up the right dose themselves.

In fact, in 2004 the American College of Obstetricians and Gynecologists issued guidelines calling the combination a first-line therapy.

The difference that prescription-only Diclegis would offer: Combining both ingredients with a delayed-release coating designed to help women take a daily dose before their nausea sets in.

The return of an FDA-cleared treatment is needed, said ACOG spokesman Dr. Jeffrey Ecker, an obstetrician at Massachusetts General Hospital who wasn't involved in the study of Diclegis.

"It's not magic," Ecker cautioned, saying few women see their symptoms completely disappear with the medication. "But for some it allows them to be much more functional."

In Hankins' study, about 260 U.S. women with morning sickness were given either Diclegis or a dummy pill for two weeks. The Diclegis users missed on average 1 1/2 fewer days of work than their counterparts.

Duchesnay wouldn't reveal a U.S. price.

About three-quarters of women experience at least some nausea and vomiting with the hormonal surges of early pregnancy. Although it often occurs upon waking, some women have trouble all day. It usually ends by the second trimester.

About 1 percent of women undergo dangerously severe vomiting called hyperemesis gravidarum, the condition that made headlines last December when in Britain, Prince William's wife Kate was briefly hospitalized.

An initial version of Bendectin began selling in 1956, and 33 million women around the world were estimated to have taken it before the lawsuits began. At the time, the FDA continued to call the drug safe; appeals courts ruled in favor of Bendectin maker Merrell Dow Pharmaceuticals; and eventually a U.S. Supreme Court decision would render continuing suits unlikely. But Merrell Dow declared the litigation cost too high, and quit making Bendectin in 1983.

What happened? The government estimates 1 in 33 babies are born with birth defects regardless of medication use during pregnancy, and studies eventually concluded that Bendectin didn't increase that baseline risk. McCabe of the March of Dimes says it's important to recognize that when a drug is widely used in pregnancy, some babies will be born with birth defects that are a coincidence.

Doctors advise trying some other steps before turning to medication for morning sickness: Eat protein snacks before bed. Nibble crackers or sip ginger ale before getting out of bed. Eat frequent small meals. Avoid nausea-triggering odors.

When that doesn't work, Ecker says vitamin B6 alone helps some women. His next step is the B6-and-antihistamine combination that will form Diclegis. A next-step option includes the drug Zofran, normally used to treat nausea from cancer therapy.

© 2013 THE ASSOCIATED PRESS. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED. Learn more about our PRIVACY POLICY and TERMS OF USE.