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   IMPERIAL, Mo. (AP) - The Missouri Highway Patrol says two drivers were killed in a head-on crash when one of them drove north in the southbound lanes of a highway south of St. Louis.
   The crash happened shortly after noon Tuesday on Missouri Hwy. 21 in Jefferson County.
   Investigators said 82 year old Mary E. Burke, of St. Louis, mistakenly entered the southbound lanes. Her car eventually collided with a pickup truck driven by 25 year old James R. Sybert, of De Soto. Burke was pronounced dead at the scene, and Sybert died at a hospital.
   Police said Burke may have driven as far as four miles in the wrong direction.
 
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