Health & Fitness (60)
Last week, the coronavirus related to SARS spread to France, where one patient who probably caught the disease in Dubai infected his hospital roommate. Officials are now trying to track down everyone who went on a tour group holiday to Dubai with the first patient as well as all contacts of the second patient. Since it was first spotted last year, the new coronavirus has infected 34 people, killing 18 of them. Nearly all had some connection to the Middle East.
The World Health Organization, however, says there is no reason to think the virus is restricted to the Middle East and has advised health officials worldwide to closely monitor any unusual respiratory cases.
At the same time, a new bird flu strain, H7N9, has been infecting people in China since at least March, causing 32 deaths out of 131 known cases.
WHO, which is closely monitoring the viruses, says both have the potential to cause a pandemic - a global epidemic - if they evolve into a form easily spread between people. Here's a crash course in what we know so far about them:
Q: How are humans getting infected by the new coronavirus?
A: Scientists don't exactly know. There is some suggestion the disease is jumping directly from animals like camels or goats to humans, but officials are also considering other sources, like a common environmental exposure. The new coronavirus is most closely related to a bat virus, but it's possible that bats are transmitting the disease via another source before humans catch it.
Q: Can the new coronavirus be spread from human to human?
A: In some circumstances, yes. There have been clusters of the disease in Saudi Arabia, Jordan, Britain and now France, where the virus has spread from person-to-person. Most of those infected were in very close contact, such as people taking care of a sick family member or health workers treating patients. There is no evidence the virus is spreading easily between people and all cases of human-to-human transmission have been limited so far.
Q: How are people catching the bird flu H7N9?
A: Some studies suggest the new bird flu is jumping directly to people from poultry at live bird markets. Cases have slowed down since Chinese authorities began shutting down such markets. But it's unclear exactly what kind of exposure is needed for humans to catch the virus and very few animals have tested positive for it. Unlike the last bird flu strain to cause global concern, H5N1, the new strain doesn't appear to make birds sick and may be spreading silently in poultry populations.
Q: What precautions can people take against these new viruses?
A: WHO is not advising people to avoid traveling to the Middle East or China but is urging people to practice good personal hygiene like regular hand-washing. "Until we know how and where humans are contracting these two diseases, we cannot control them," said Gregory Hartl, WHO spokesman.
Q: Which virus should we be more worried about?
A: It's impossible to know. "We really don't want to play the game of predicting which virus will be more deadly than the other," Hartl said. At the moment, both are worrisome since so little is known about how they are infecting humans and both appear to cause severe disease. "Any virus that has the ability to develop the capacity to spread from human to human is of great concern to WHO," he said.
The stakes are high for Christie, with medical professionals and campaign strategists alike suggesting there is no more serious barrier to his personal well-being and national ambitions than his weight.
It's not about politics, he said. It's about turning 50 and wanting to be around as his children grow up.
"This is a hell of a lot more important to me than running for president," Christie, a father of four, said at a news conference in Newark. "This is about my family's future."
Christie, who appeared thinner than he did earlier this year, said he decided around the time of his birthday in September to have the surgery and initially planned to have it done in November. But Superstorm Sandy's destruction in New Jersey pushed back the procedure until February. In the operation, a band was surgically placed around his stomach to restrict how much food he could eat.
Christie has not previously disclosed his weight, and he didn't on Tuesday. But it has been an issue throughout his political career. Comedians have often made fun of it, and in interviews with David Letterman, Oprah Winfrey, Barbara Walters and others, Christie has both joked about the issue and said solemnly that he was trying to shed pounds.
During a February appearance on "The Late Show with David Letterman," the governor pulled out a doughnut and said his girth was "fair game" for comedians.
Over the next few days, he was asked repeatedly about his weight. At one point, he said he had a plan. "Whether it's successful or not," he said, "you'll all be able to notice."
The next day, he responded angrily to comments from a former White House physician who said she hoped he would run for president but worried about him dying in office. The governor said the doctor should "shut up."
Ten days after that, on Feb. 16, Christie had the surgery. He said the operation lasted 40 minutes and he was home the same afternoon. He was back at work on Feb. 19 for a full day of events.
Christie, who is in the midst of a re-election campaign, said he has been eating less because he hasn't been as hungry. He also has been working out with a personal trainer.
He said he had told only a few top staffers - not his communications office or campaign staff - and his communications director was caught by surprise Monday when a New York Post reporter asked directly if he'd had the procedure. The Post first reported the surgery on Tuesday. Christie said he'd used an alias at the hospital.
Christie said he never intended to make a public announcement and that he was "not going to be the guy who writes a book" about losing weight. The Republican, who has been a fixture in the national media spotlight, said the scrum of reporters at his news conference was "silly" and "ridiculous" at a time when there are other things going on.
He said he tried other ways to lose weight for years, but none seemed to work.
"It's not a career issue for me; it's a long-term health issue for me," he said.
Still, it's a way to confront a significant hurdle in his indisputable quest to emerge as a key leader in the Republican Party. He's in the top tier of those considered potential contenders for the presidential nomination in 2016.
Weeks after the surgery, Christie launched an aggressive national fundraising tour, fueling speculation that he's laying the groundwork for a White House bid.
In a country facing an obesity epidemic, more than 220,000 stomach-reducing procedures of various types are performed each year. Gastric bypass, sometimes called stomach stapling, is the most common, where surgeons shrink the stomach's size and reroute food to the small intestine. Christie had gastric band surgery. It's best known by the brand name Lap-Band, and is a less invasive alternative in which an adjustable ring is placed over the top of the stomach and tightened to restrict how much food can enter.
The adjustable Lap-Band has been available in the U.S. since 2001 for the most obese patients, and in 2011 the Food and Drug Administration expanded approval to somewhat less obese patients.
Candidates for gastric banding must have a body mass index of between 30 and 40 - plus a weight-related medical condition, such as diabetes or high blood pressure - or a BMI of 40 and higher. They also must have previously attempted to lose weight through diet and exercise.
"If you eat appropriately and chew your food, it works nicely," said Dr. Christina Li, a bariatric doctor at Sinai Hospital of Baltimore. She said Christie has the resources to have people help him eat right and get exercise. While the band is removable, she said patients are told to adjust to having it for the rest of their lives.
Li said risks include infection, and that it does not work for all patients.
Dr. Jaime Ponce, who practices in Dalton, Ga., and is president of the American Society for Metabolic & Bariatric Surgery, said people who have the procedure Christie had often lose 1 to 2 pounds per week.
Christie's procedure was performed by Dr. George Fielding, head of NYU Medical Center's Weight Management Program, who did the same procedure for New York Jets coach Rex Ryan three years ago.
"It basically teaches you how to eat like a human," Ryan said of the device in an interview last week with The Associated Press. "The Lap-Band goes: `No, no. You're only going to eat this or that,' and it trains your body how to eat right," said Ryan, who said he has lost 115 pounds from his pre-surgery weight of 348.
Few significantly overweight presidential candidates have succeeded in the modern political era, when television became a major factor in shaping voter attitudes. There are disputed reports that President William Howard Taft couldn't fit in a White House bathtub a century ago, but only a handful of presidents since have been considered obese. President Bill Clinton struggled at times with his weight, but he was substantially slimmer than the New Jersey governor.
"This has nothing to do with politics," said Christie adviser Bill Palatucci. "He said that he's doing this for his family and that's the right reason."
Backers publicly argue that Christie answered any questions about his weight's political impact in 2009, when he beat Gov. Jon Corzine despite the Democrat's reference in an ad to Christie "throwing his weight around" to get out of traffic tickets. Supporters say Christie's openness about his struggle is part of an authenticity people admire in him.
The governor's allies, medical professionals and even history suggest that his weight presents both practical and political problems.
"Gov. Christie's weight is an issue the same way that any candidate or official's health is an issue," said Michael Dennehy, a New Hampshire-based Republican strategist and veteran of presidential politics. "Anyone running for president will need to comfort Americans with an overall healthy picture for their future."
Mulvihill reported from Haddonfield, N.J., and Peoples from Providence, R.I. AP Medical Writer Lauran Neergaard in Washington, AP writers Thomas Beaumont in Des Moines, Iowa, and AP Sports Writer Dennis Waszak in New York contributed to this report.
The company says that people who received 18 months of infusions with its drug, Gammagard, fared no better than others given infusions of a dummy solution.
Gammagard is immune globulin, natural antibodies culled from donated blood. Researchers thought these antibodies might help remove amyloid, the sticky plaque that clogs patients' brains, sapping memory and ability to think.
Patients with moderate disease and those with a gene that raises risk of Alzheimer's who were taking the higher of two doses in the study seemed to benefit, although the study was not big enough to say for sure.
"The study missed its primary endpoints, however we remain interested by the prespecified sub-group analyses" in groups that seemed to benefit, Ludwig Hantson, president of Baxter's BioScience business, said in a statement.
Gammagard is already sold to treat some blood disorders, and the results of the Alzheimer's study do not affect those uses. About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.
Excitement about Gammagard grew last summer, when researchers reported at a medical conference that the drug had stabilized Alzheimer's disease for as much as three years in four patients who had been receiving the highest dose of it for three years in the study. People typically go from diagnosis to death in about eight years, so to be stable for so long was considered remarkable.
The new results on the full group of study participants are disappointing, said the study's leader, Dr. Norman Relkin, head of a memory disorders program at New York-Presbyterian Hospital/Weill Cornell Medical Center.
"The bar was set very high" for the drug to show improvement, and "there does appear to be a signal" that it helped the two-thirds of patients in the study who had the apoE4 gene that raises the risk of developing Alzheimer's, as well as those with moderate versus mild disease, Relkin said.
No new side effects were seen in the study. About 5 percent of patients on the drug had a rash and decreases in hemoglobin, which carries oxygen in the blood. There were 17 serious reactions, 12 in the drug group and five in the placebo group.
Full results will be presented in July at an Alzheimer's conference in Boston.
Meanwhile, other studies are under way to test drugs earlier in the course of the disease. An experimental drug, Eli Lilly & Co.'s solanezumab, showed some promise in that setting in an earlier study.
Shares of Baxter fell $2.53, or 3.6 percent, to $67.78 in morning trading.
The FDA has regulated tanning beds and sun lamps for over 30 years, but for the first time ever the agency says those devices should not be used by people under age 18. The agency wants that warning on pamphlets, catalogues and websites that promote indoor tanning. And regulators are also proposing that manufacturers meet certain safety and design requirements, including timers and limits on radiation emitted.
The government action is aimed at curbing cases of melanoma, the deadliest form of skin cancer, which have been on the rise for about 30 years. An estimated 2.3 million U.S. teenagers tan indoors each year, and melanoma is the second most common form of cancer among young adults, according to the American Academy of Dermatology.
Recent studies have shown that the risk of melanoma is 75 percent higher in people who have been exposed to ultraviolet radiation from indoor tanning. While most cases are diagnosed in people in their 40s and 50s, the disease is linked to sun exposure at a young age.
Physician groups have been urging the U.S. government to take action on tanning beds for years, citing increases in the number of cases of skin cancer among people in their teens and 20s.
"As a dermatologist I see the consequences of indoor tanning. I have to diagnose too many young people with melanoma and see the grief that it causes to these families," said Dr. Mary Maloney of the American Academy of Dermatology, on a call with FDA officials. Maloney said the FDA action is an important first step, but that her group would continue to push for a ban on the sale and use of tanning beds for people under age 18.
Earlier this year, a study of Missouri tanning salons found that 65 percent of 250 businesses surveyed would accept children ages 10 to 12, often without parental permission. The study was conducted by dermatologists at the Washington University School of Medicine in St. Louis.
Currently the machines are classified as low-risk devices, in the same group as bandages and tongue depressors. The proposal would increase their classification to moderate-risk, or class II, devices. That would allow the FDA to review their safety and design before manufacturers begin selling them.
"They don't have to provide any data in advance before they go on the market, so we have no way of providing assurance that the tanning beds are performing up to specifications," said Dr. Jeffrey Shuren, FDA's director for medical devices.
Safety standards are important because recent studies show that many devices can cause sunburn even when used as directed. A 2009 study found that 58 percent of adolescents who tan indoors had sunburn exposure.
"If you get an indoor tan you shouldn't be burning," Shuren said.
The Indoor Tanning Association said it supported any changes that improve its customers' safety. But, in a statement, the group added that "we are concerned that these changes will burden our members with addition unnecessary governmental costs in an already difficult economic climate."
The FDA proposal would not place warnings on the devices themselves, but on related promotional material and websites. Some consumer advocates said those warnings might never actually reach users.
"The FDA is requiring that the labels and pamphlets include risk information about skin cancer, but consumers would not be required to see those labels or pamphlets - they are apparently only for the company buying the tanning bed," said Diana Zuckerman, of the National Research Center for Women and Families.
The agency said it will take comments on its proposal for 90 days before formulating a final regulation. Agency officials didn't give a timeframe for completion, but said it would be a priority.
TRENTON, N.J. (AP) - Men who are bashful about needing help in the bedroom no longer have to visit a drugstore to buy that little blue pill.
In a first for the drug industry, Pfizer Inc. says starting today it will sell begin selling erectile dysfunction pill Viagra directly to patients on its website.
Men still will need a prescription to buy the blue pill on viagra.com, but they won't have to face a pharmacist to get it filled.
Other drugmakers likely will watch closely, and could begin selling other medicines online.'
The trend was most pronounced among white men and women in that age group. Their suicide rate jumped 40 percent between 1999 and 2010.
But the rates in younger and older people held steady. And there was little change among middle-aged blacks, Hispanics and most other racial and ethnic groups, the report from the Centers for Disease Control and Prevention found.
Why did so many middle-aged whites - that is, those who are 35 to 64 years old - take their own lives?
One theory suggests the recession caused more emotional trauma in whites, who tend not to have the same kind of church support and extended families that blacks and Hispanics do.
The economy was in recession from the end of 2007 until mid-2009. Even well afterward, polls showed most Americans remained worried about weak hiring, a depressed housing market and other problems.
Pat Smith, violence-prevention program coordinator for the Michigan Department of Community Health, said the recession - which hit manufacturing-heavy states particularly hard - may have pushed already-troubled people over the brink. Being unable to find a job or settling for one with lower pay or prestige could add "that final weight to a whole chain of events," she said.
Another theory notes that white baby boomers have always had higher rates of depression and suicide, and that has held true as they've hit middle age. During the 11-year period studied, suicide went from the eighth leading cause of death among middle-aged Americans to the fourth, behind cancer, heart disease and accidents.
"Some of us think we're facing an upsurge as this generation moves into later life," said Dr. Eric Caine, a suicide researcher at the University of Rochester.
One more possible contributor is the growing sale and abuse of prescription painkillers over the past decade. Some people commit suicide by overdose. In other cases, abuse of the drugs helps put people in a frame of mind to attempt suicide by other means, said Thomas Simon, one of the authors of the CDC report, which was based on death certificates.
People ages 35 to 64 account for about 57 percent of suicides in the U.S.
The report contained surprising information about how middle-aged people kill themselves: During the period studied, hangings overtook drug overdoses in that age group, becoming the No. 2 manner of suicide. But guns remained far in the lead and were the instrument of death in nearly half of all suicides among the middle-aged in 2010.
The CDC does not collect gun ownership statistics and did not look at the relationship between suicide rates and the prevalence of firearms.
For the entire U.S. population, there were 38,350 suicides in 2010, making it the nation's 10th leading cause of death, the CDC said. The overall national suicide rate climbed from 12 suicides per 100,000 people in 1999 to 14 per 100,000 in 2010. That was a 15 percent increase.
For the middle-aged, the rate jumped from about 14 per 100,000 to nearly 18 - a 28 percent increase. Among whites in that age group, it spiked from about 16 to 22.
Suicide prevention efforts have tended to concentrate on teenagers and the elderly, but research over the past several years has begun to focus on the middle-aged. The new CDC report is being called the first to show how the trend is playing out nationally and to look in depth at the racial and geographic breakdown.
Thirty-nine out of 50 states registered a statistically significant increase in suicide rates among the middle-aged. The West and the South had the highest rates. It's not clear why, but one factor may be cultural differences in willingness to seek help during tough times, Simon said.
Also, it may be more difficult to find counseling and mental health services in certain places, he added.
Suicides among middle-aged Native Americans and Alaska Natives climbed 65 percent, to 18.5 per 100,000. However, the overall numbers remain very small - 171 such deaths in 2010. And changes in small numbers can look unusually dramatic.
The CDC did not break out suicides of current and former military service members, a tragedy that has been getting increased attention. But a recent Department of Veterans Affairs report concluded that suicides among veterans have been relatively stable in the past decade and that veterans have been a shrinking percentage of suicides nationally.
--- Associated Press writer Jeff Karoub in Detroit contributed to this report.
Air quality forecasting officially begins Wednesday for the 2013 summer season, and St. Louis residents will want to pay attention in order to protect their health.
Officials with the American Lung Association say that's because the air in St. Louis is getting worse. Their latest State of the Air report shows the Gateway City is now ranked 25th worst in the nation for ozone pollution. We were 34th last year.
And St. Louis is 12th when it comes to year round particulate pollution. That's a slight improvement over our 10th place finish last year. But officials say it still means St. Louis is among the most polluted metropolitan areas in the nation.
Residents who want to receive air quality updates by email, can sign up at the Clean Air St. Louis website.